2-[5-Fluoro-2-(phenylmethoxy)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane → 4-Fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol

HRID 1694756Notes

Reaction equation

HRID 1694756 reaction equation
[F:1][C:2]1[CH:3]=[CH:4][C:5]([O:17]CC2C=CC=CC=2)=[C:6]([B:8]2[O:12][C:11]([CH3:14])([CH3:13])[C:10]([CH3:16])([CH3:15])[O:9]2)[CH:7]=1>C(O)C>[F:1][C:2]1[CH:3]=[CH:4][C:5]([OH:17])=[C:6]([B:8]2[O:12][C:11]([CH3:14])([CH3:13])[C:10]([CH3:16])([CH3:15])[O:9]2)[CH:7]=1

Participants

3

Reactant 1

HCID 672806532-[5-Fluoro-2-(phenylmethoxy)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Product 1

HCID 567377034-Fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

The subtitle compound was prepared by the method of example 146 step (ii) using the product from step (iii) and ethanol as solvent.

Sources & evidence

ORD record
ord-e768ed50baf34269a1f6f01e8380645a
Source dataset
uspto-grants-2012_04
Patent number
US08158820B2

Reaction notes

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