HCID 11372382, compound → [[4'-(Methylthio)-2',5-bis(trifluoromethyl)[1,1'-biphenyl]-2-yl]oxy]acetic acid, 1,1-dimethylethyl ester

HRID 1694759Notes

Reaction equation

HRID 1694759 reaction equation
CC1(C)C(C)(C)OB(C2C=CC(SC)=C([C:17]([F:20])([F:19])[F:18])C=2)O1.[CH2:22]([S:24]([C:27]1[CH:32]=[CH:31][C:30]([C:33]2[C:38](C)=[C:37]([N+]([O-])=O)[CH:36]=[CH:35][C:34]=2[O:43][CH2:44][C:45]([OH:47])=[O:46])=[CH:29][CH:28]=1)(=O)=O)C>>[CH3:22][S:24][C:27]1[CH:28]=[CH:29][C:30]([C:33]2[CH:38]=[C:37]([C:17]([F:20])([F:19])[F:18])[CH:36]=[CH:35][C:34]=2[O:43][CH2:44][C:45]([O:47][C:30]([CH3:33])([CH3:31])[CH3:29])=[O:46])=[C:31]([C:17]([F:18])([F:19])[F:20])[CH:32]=1

Participants

3

Reactant 2

HCID 11372382HCID 11372382, compoundHCID 672773014-Methylthio-3-(trifluoromethyl)phenylboronic acid pinacol ester

Product 1

HCID 86609223[[4'-(Methylthio)-2',5-bis(trifluoromethyl)[1,1'-biphenyl]-2-yl]oxy]acetic acid, 1,1-dimethylethyl ester

Procedure

The title compound was prepared by the method of example 1 step (ii) using the products from steps (ii) and (iii). Yield 0.564 g. Carried forward to step (v) without characterisation.

Sources & evidence

ORD record
ord-a268e172aa9e4b8b901b4b8057fbd33d
Source dataset
uspto-grants-2012_04
Patent number
US08158820B2

Reaction notes

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