HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 67281054, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | 2-Chloromethyl 2-(trimethylsilyl)ethyl ether | HCID 2724271 | — |
| Reactant | HCID 67280005 | HCID 67280005 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 67281054 | HCID 67281054 | — |
Reaction Steps
[2-(Chloromethoxy)ethyl]trimethylsilane (0.4 ml) was added to a solution of the product from step (i) in DMF (10 ml) and stirred for 20 min. The mixture was poured into water, extracted with ether, washed with brine, dried (MgSO4) and evaporated. The residue was purified by chromatography on silica eluting with 20% EtOAc/isohexane. Yield 0.53 g.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08158820B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-0c5e822f25fc439293d64d30115490fa |
| Source note | uspto-grants-2012_04 |