HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 178436309, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | Triethylsilane | HCID 12052 | — |
| Reactant | HCID 58951969 | HCID 58951969 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 178436309 | HCID 178436309 | — |
Reaction Steps
Prepared in analogy to Example 57(e) from rac-2-(tert-butyl-dimethyl-silanyl)-4-[(2-ethyl-6-fluoro-phenyl)-hydroxy-methyl]-imidazole-1-sulfonic acid dimethylamide, triethylsilane and trifluoroacetic acid in dichloromethane in a pressure tube at 100° C. for 16 h. White crystalline solid. MS (ISP): 205.3 ([M+H]+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08158668B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-31a1eff4e0994599a038093148fd4beb |
| Source note | uspto-grants-2012_04 |