Pentanoyl chloride, 4-methyl- → (S)-4-Benzyl-3-(4-methylpentanoyl)oxazolidin-2-one

HRID 1695027Notes

Reaction equation

HRID 1695027 reaction equation
[CH2:1]([C@H:8]1[CH2:12][O:11][C:10](=[O:13])[NH:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:14][CH:15]([CH3:21])[CH2:16][CH2:17][C:18](Cl)=[O:19]>>[CH2:1]([C@H:8]1[CH2:12][O:11][C:10](=[O:13])[N:9]1[C:18](=[O:19])[CH2:17][CH2:16][CH:15]([CH3:21])[CH3:14])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 170008Pentanoyl chloride, 4-methyl-HCID 736225(S)-4-Benzyl-2-oxazolidinone

Product 1

HCID 10869526(S)-4-Benzyl-3-(4-methylpentanoyl)oxazolidin-2-one

Procedure

27.1 g of the crude title compound (yield: quant.) was obtained in the same manner as in Reference Example 5 using (S)-4-benzyl-2-oxazolidinone and 4-methylpentanoyl chloride.

Sources & evidence

ORD record
ord-689c3176cafc498088997c4426007b4f
Source dataset
uspto-grants-2012_04
Patent number
US08158790B2

Reaction notes

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