Morpholine → 4-[(4-Bromo-2,5-difluorophenyl)sulfonyl]-morpholine

関与物質

反応手順

Morpholine (0.16 ml) was added to a stirred solution of 4-bromo-2,5-difluoro-benzenesulfonyl chloride (0.18 g) in dichloromethane (6 ml) under nitrogen. The reaction mixture was stirred overnight and then quenched with water. The organic phase was dried (MgSO4) and concentrated in vacuo to give the sub-title compound as a white solid (200 mg).

情報源と証拠