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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1695138Generated: October 26, 2026

Isoxazolidine → 2-[(3,5'-Dichloro-2'-methoxy[1,1'-biphenyl]-4-yl)carbonyl]-isoxazolidine

https://huagongshe.com/reaction/1695138

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIsoxazolidineHCID 136333—
Reactant[[3',5-dichloro-4'-[[(2R,6S)-2,6-dimethyl-1-piperidinyl]carbonyl][1,1'-biphenyl]-2-yl]oxy]-acetic acidHCID 11517726—
Product2-[(3,5'-Dichloro-2'-methoxy[1,1'-biphenyl]-4-yl)carbonyl]-isoxazolidineHCID 68606357—

Reaction Steps

The sub-title compound was prepared by the method of example 21 step b) using the product of example 21 step a) and isoxazolidine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08163727B2
Source datasetuspto-grants-2012_04
ORD IDord-f5d310692fc14d16ae56e973b8733c6c
Source noteuspto-grants-2012_04