Diisopropylamine → 4-bromo-2-fluoro-N,N-bis(1-methylethyl)-benzamide

HRID 1695145Notes

Reaction equation

HRID 1695145 reaction equation
[Br:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([OH:8])=O)=[C:4]([F:11])[CH:3]=1.[CH:12]([NH:15][CH:16]([CH3:18])[CH3:17])([CH3:14])[CH3:13]>>[Br:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([N:15]([CH:16]([CH3:18])[CH3:17])[CH:12]([CH3:14])[CH3:13])=[O:8])=[C:4]([F:11])[CH:3]=1

Participants

3

Reactant 2

HCID 7912DiisopropylamineHCID 3026814-Bromo-2-fluorobenzoic acid

Product 1

HCID 672771854-bromo-2-fluoro-N,N-bis(1-methylethyl)-benzamide

Procedure

The sub-title compound was prepared by the method of example 18 step a) using 4-bromo-2-fluorobenzoic acid and diisopropylamine.

Sources & evidence

ORD record
ord-205eb0b3ec824abebf5d2fd44eadcd72
Source dataset
uspto-grants-2012_04
Patent number
US08163727B2

Reaction notes

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