N-Methylethylamine → 4-bromo-N-ethyl-2-fluoro-N-methylbenzamide

HRID 1695147Notes

Reaction equation

[Br:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([OH:8])=O)=[C:4]([F:11])[CH:3]=1.[CH3:12][NH:13][CH2:14][CH3:15]>>[Br:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([N:13]([CH2:14][CH3:15])[CH3:12])=[O:8])=[C:4]([F:11])[CH:3]=1

Participants

Reactant 2

HCID 12219N-Methylethylamine

HCID 3026814-Bromo-2-fluorobenzoic acid

Product 1

HCID 432434194-bromo-N-ethyl-2-fluoro-N-methylbenzamide

Procedure

The sub-title compound was prepared by the method of example 18 step a) using 4-bromo-2-fluorobenzoic acid and N-methyl-ethanamine.

Sources & evidence

ORD record: ord-f9a195b9dd5d4931a29f5c91d2380f80
Source dataset: uspto-grants-2012_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08163727B2

Reaction notes

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