1-Iodopentane → HCID 86645805, compound

HRID 1695167Notes

Reaction equation

[C:1]([O:5][C:6](=[O:16])[CH2:7][C@H:8]([OH:15])[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH3:14])([CH3:4])([CH3:3])[CH3:2].I[CH2:18][CH2:19][CH2:20][CH2:21][CH3:22]>>[C:1]([O:5][C:6](=[O:16])[C@@H:7]([CH2:18][CH2:19][CH2:20][CH2:21][CH3:22])[C@@H:8]([OH:15])[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH3:14])([CH3:2])([CH3:4])[CH3:3]

Participants

Reactant 2

HCID 123351-Iodopentane

HCID 86645804HCID 86645804, compound

Product 1

HCID 86645805HCID 86645805, compound

Procedure

The target compound (2.00 g, 31%) was obtained in the same manner as in Production Example C-1, except that the (R)-3-hydroxynonanoic acid t-butyl ester (5.00 g, 21.7 mmol) obtained in Production Example B-3 and 1-iodopentane (5.59 g, 28.2 mmol) were used.

Sources & evidence

ORD record: ord-14de5ffe58134d97bf2987e604c0b39e
Source dataset: uspto-grants-2012_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08163713B2

Reaction notes

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