HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Carbomethoxypyridine → Pyridine-2-carbonyl cyanide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Carbomethoxypyridine | HCID 75569 | — |
| Reactant | HCID 67015924 | HCID 67015924 | — |
| Reactant | HCID 178418806 | HCID 178418806 | — |
| Product | Pyridine-2-carbonyl cyanide | HCID 13111406 | 69% |
Reaction Steps
The product was prepared according to the general procedure for aminopyrazole synthesis (route A1) from pyridine-2-carboxylic acid methyl ester (3.0 g, 21.9 mmol, 1.0 eq). The crude was precipitated from HCl to give the title product as a solid (2.2 g, yield: 69%) which was used directly for the next step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08163729B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-8270d9723ff84f818045659c2539cfe3 |
| Source note | uspto-grants-2012_04 |