反应详情

3.0 g of 4-isopropoxy-benzoic acid (16.7 mmol, 1.0 eq) were dissolved in MeOH (20 mL) and a catalytic quantity of sulfuric acid was added; the mixture was heated at reflux for 2 days. The solvent was then evaporated and the residue was dissolved in DCM and washed with 10% NaOH. The organic phases were dried and evaporated to give 2.2 g of title product (yield 67%).

1. temperaturethe mixture was heated
2. temperatureat reflux for 2 days
3. customThe solvent was then evaporated
4. dissolutionthe residue was dissolved in DCM
5. washwashed with 10% NaOH
6. customThe organic phases were dried
7. customevaporated