5-(N-methyl-3-tert-butoxycarbonylaminopropyn-1-yl)-benzene-1,3-dicarboxylic acid diethyl ester → 5-(N-methyl-3-tert-butoxycarbonylaminopropyl)-benzene-1,3-dicarboxylic acid diethyl ester

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To a solution of 5-(N-methyl-3-tert-butoxycarbonylaminopropyn-1-yl)-benzene-1,3-dicarboxylic acid diethyl ester (890 mg) in methanol (10 mL) was added palladium 10% on carbon (89 mg) and the solution was stirred at room temperature under an hydrogen atmosphere (1 bar) for 18 h. The solid was filtered off and solvent was removed in vacuo to afford 5-(N-methyl-3-tert-butoxycarbonylaminopropyl)-benzene-1,3-dicarboxylic acid diethyl ester (767 mg) as a yellow oil:

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