HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isopropylamine → 5-(5-Methyl-3-phenyl-isoxazol-4-ylmethoxy)-2H-pyrazole-3-carboxylic acid isopropylamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isopropylamine | HCID 6363 | — |
| Reactant | HCID 66643884 | HCID 66643884 | — |
| Product | 5-(5-Methyl-3-phenyl-isoxazol-4-ylmethoxy)-2H-pyrazole-3-carboxylic acid isopropylamide | HCID 49793241 | 13% |
Reaction Steps
As described for example 1b, 5-(5-methyl-3-phenyl-isoxazol-4-ylmethoxy)-2H-pyrazole-3-carboxylic acid methyl ester (100 mg, 0.32 mmol) was converted, using isopropylamine instead of morpholine, to the title compound (14 mg, 13%), which was obtained as a colorless oil. MS: m/e=341.3 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08163728B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-2290a58aa45848ddb2600884070cdd36 |
| Source note | uspto-grants-2012_04 |