HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,1-Dimethylhydrazine → 5-(5-Methyl-3-phenyl-isoxazol-4-ylmethoxy)-2H-pyrazole-3-carboxylic acid N',N'-dimethyl-hydrazide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,1-Dimethylhydrazine | HCID 5976 | — |
| Reactant | HCID 66643884 | HCID 66643884 | — |
| Product | 5-(5-Methyl-3-phenyl-isoxazol-4-ylmethoxy)-2H-pyrazole-3-carboxylic acid N',N'-dimethyl-hydrazide | HCID 49793240 | 24% |
Reaction Steps
As described for example 1b, 5-(5-methyl-3-phenyl-isoxazol-4-ylmethoxy)-2H-pyrazole-3-carboxylic acid methyl ester (100 mg, 0.32 mmol) was converted, using N,N-dimethylhydrazine instead of morpholine, to the title compound (26 mg, 24%), which was obtained as a white solid. MS: m/e=342.1 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08163728B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-39151b5be86f4dbfaac5578eb23d9c95 |
| Source note | uspto-grants-2012_04 |