4-Aminotetrahydropyran → HCID 178434993, compound

Participants

Reaction Steps

As described for example 14e, 5-(5-methyl-3-pyridin-2-yl-isoxazol-4-ylmethoxy)-2H-pyrazole-3-carboxylic acid methyl ester (70 mg, 0.22 mmol) was converted, using 4-aminotetrahydropyran instead of isopropylamine to the title compound (85 mg, 99%), which was obtained as a colorless oil. MS: m/e=384.2 [M+H]+.

Provenance & Evidence