N-Aminomorpholine → HCID 49792870, compound

Participants

Reaction Steps

As described for example 1b, 5-[3-(5-fluoro-pyridin-2-yl)-isoxazol-4-ylmethoxy]-2H-pyrazole-3-carboxylic acid methyl ester (70 mg, 0.22 mmol), instead of 5-(5-methyl-3-phenyl-isoxazol-4-ylmethoxy)-2H-pyrazole-3-carboxylic acid methyl ester, was converted, using 4-aminomorpholine instead of morpholine, to the title compound (32 mg, 38%) which was obtained as a white solid. MS: m/e=389.1 [M+H]+.

Provenance & Evidence