Oxolan-3-amine → Rac-5-(3-butyl-5-methyl-isoxazol-4-ylmethoxy)-2-methyl-2h-pyrazole-3-carboxylic acid (tetrahydro-furan-3-yl)-amide

Participants

Reaction Steps

As described for example 86, 5-(3-butyl-5-methyl-isoxazol-4-ylmethoxy)-2-methyl-2H-pyrazole-3-carboxylic acid methyl ester (60 mg, 0.2 mmol) was converted, using rac-3-aminotetrahydrofuran instead of isopropylamine, to the title compound (54 mg, 76%) which was obtained as a colorless oil. MS: m/e=363.1 [M+H]+.

Provenance & Evidence