HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 86647276, compound → 5-[3-(4-chloro-phenyl)-5-hydroxymethyl-isoxazol-4-ylmethoxy]-2-methyl-2H-pyrazole-3-carboxylic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 86647276 | HCID 86647276 | — |
| Reactant | HCID 86761556 | HCID 86761556 | — |
| Product | 5-[3-(4-chloro-phenyl)-5-hydroxymethyl-isoxazol-4-ylmethoxy]-2-methyl-2H-pyrazole-3-carboxylic acid methyl ester | HCID 66643931 | 100% |
Reaction Steps
As described for example 91g, 5-[3-(4-chloro-phenyl)-5-formyl-isoxazol-4-ylmethoxy]-2-methyl-2H-pyrazole-3-carboxylic acid methyl ester (2.4 g, 6.6 mmol), instead of 5-[3-(4-fluoro-phenyl)-5-formyl-isoxazol-4-ylmethoxy]-2-methyl-2H-pyrazole-3-carboxylic acid methyl ester, was converted to the title compound (2.4 g, 100%) which was obtained as a white solid. MS: m/e=378.2 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08163728B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-0713d99be1ba4363a91a93c27c16603c |
| Source note | uspto-grants-2012_04 |