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HRID1695465

反应详情

EQUATION

反应方程式

HRID 1695465 的结构方程式

REACTANTS

反应物

2
结构：COC(=O)c1cc(OCc2c(-c3ccccn3)noc2C)n(C)n1
HCID66646333

未命名化合物

结构：COC(=O)c1cc(OCc2c(-c3ccc(F)cn3)noc2C)n(C)n1
HCID66646478

未命名化合物

PRODUCTS

生成物

1
结构：Cc1onc(-c2ccc(F)cn2)c1COc1cc(C(=O)N[C@@H](C)CO)nn1C
HCID66646207

未命名化合物

收率 59%

PROCEDURE

实验过程

As described for example 114d, 5-[3-(5-fluoro-pyridin-2-yl)-5-methyl-isoxazol-4-ylmethoxy]-1-methyl-1H-pyrazole-3-carboxylic acid methyl ester (100 mg, 0.29 mmol), instead of 1-methyl-5-(5-methyl-3-pyridin-2-yl-isoxazol-4-ylmethoxy)-1H-pyrazole-3-carboxylic acid methyl ester, was converted, to the title compound (66 mg, 59%) which was obtained as a colorless oil. MS: m/e=390.1 [M+H]+.