2-Aminopropanol → HCID 49793041, compound

Participants

Reaction Steps

As described for example 120 (step 4), 5-{(Z)-2-[3-(4-fluoro-phenyl)-5-methyl-isoxazol-4-yl]-vinyl}-2-methyl-2H-pyrazole-3-carboxylic acid (0.3 mmol), was converted, using 2-hydroxy-1-methylethylamine instead of isopropylamine, to the title compound (2.9 mg, 3%) which was obtained as an off white solid. MS: m/e=385.2 [M+H]+.

Provenance & Evidence