HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanamine, 2,2,2-trifluoro- → HCID 49793045, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanamine, 2,2,2-trifluoro- | HCID 9773 | — |
| Reactant | HCID 66643882 | HCID 66643882 | — |
| Product | HCID 49793045 | HCID 49793045 | 64% |
Reaction Steps
As described for example 122, 5-{(E)-2-[3-(4-fluoro-phenyl)-5-methyl-isoxazol-4-yl]-vinyl}-2-methyl-2H-pyrazole-3-carboxylic acid was converted, using 2,2,2-trifluoroethylamine instead of isopropylamine, to the title compound (30 mg, 64%) which was obtained as a white solid. MS: m/e=409.0 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08163728B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-8e1c6c09a5314f04b2885a4297349fc5 |
| Source note | uspto-grants-2012_04 |