2-Aminopropanol → HCID 49793046, compound

Participants

Reaction Steps

As described for example 122, 5-{(E)-2-[3-(4-fluoro-phenyl)-5-methyl-isoxazol-4-yl]-vinyl}-2-methyl-2H-pyrazole-3-carboxylic acid was converted, using 2-hydroxy-1-methylethylamine instead of isopropylamine, to the title compound (6.7 mg, 17%) which was obtained as an off white solid. MS: m/e=385.2 [M+H]+.

Provenance & Evidence