HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Propanol, 1-amino-2-methyl- → HCID 178435000, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Propanol, 1-amino-2-methyl- | HCID 95102 | — |
| Reactant | HCID 178435004 | HCID 178435004 | — |
| Product | HCID 178435000 | HCID 178435000 | 26% |
Reaction Steps
As described for example 132, 5-{(E)-2-[3-(4-fluoro-phenyl)-5-methyl-isoxazol-4-yl]-vinyl}-2H-pyrazole-3-carboxylic acid was converted, using 2-hydroxy-2-methyl-propylamine instead of morpholine, to the title compound (9.1 mg, 26%) which was obtained as a brown solid. MS: m/e=385.2 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08163728B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-f7aac04277214cff89928baf082377c5 |
| Source note | uspto-grants-2012_04 |