HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → HCID 178434996, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | HCID 178435004 | HCID 178435004 | — |
| Product | HCID 178434996 | HCID 178434996 | 32% |
Reaction Steps
As described for example 132, 5-{(E)-2-[3-(4-fluoro-phenyl)-5-methyl-isoxazol-4-yl]-vinyl}-2H-pyrazole-3-carboxylic acid was converted, using ammonia instead of morpholine, to the title compound (12 mg, 32%) which was obtained as an off white solid. MS: m/e=313.2 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08163728B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-a00f6b36e7244164926124328dfb1861 |
| Source note | uspto-grants-2012_04 |