Ethanamine, 2,2,2-trifluoro- → HCID 59568415, compound

Participants

Reaction Steps

As described for example 144, 5-{[3-(4-fluoro-phenyl)-5-methyl-isoxazol-4-ylmethyl]-amino}-2-methyl-2H-pyrazole-3-carboxylic acid was converted, using 2,2,2-trifluoro-ethylamine instead of 2-hydroxy-2-methylpropylamine, to the title compound (22 mg, 20%) which was obtained as an off white solid. MS: m/e=412.4 [M+H]+.

Provenance & Evidence