反应详情

As described for example 152, 5-{[3-(4-fluoro-phenyl)-5-methyl-isoxazol-4-ylmethyl]-amino}-2H-pyrazole-3-carboxylic acid was converted, using ethylamine instead of 2-hydroxy-2-methypropylamine, to the title compound (14 mg, 41%) which was obtained as an off white solid. MS: m/e=344.2 [M+H]+.