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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1695504Generated: October 30, 2026

4-Aminotetrahydropyran → HCID 59568449, compound

https://huagongshe.com/reaction/1695504

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-AminotetrahydropyranHCID 419223—
ReactantHCID 66646518HCID 66646518—
ProductHCID 59568449HCID 5956844996%

Reaction Steps

As described for example 160c, 1-methyl-3-((5-methyl-3-(pyridin-2-yl)isoxazol-4-yl)methylamino)-1H-pyrazole-5-carboxylic acid (14 mg; 44.7 μmol) was converted, using 4-aminotetrahydropyran instead of isopropylamine, to the title compound (17 mg, 96%) which was obtained as a white solid. MS: m/e=397.2 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08163728B2
Source datasetuspto-grants-2012_04
ORD IDord-ee724858cbea4661b337828d9f098401
Source noteuspto-grants-2012_04