HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Aminotetrahydropyran → HCID 59568440, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Aminotetrahydropyran | HCID 419223 | — |
| Reactant | HCID 66646190 | HCID 66646190 | — |
| Product | HCID 59568440 | HCID 59568440 | 80% |
Reaction Steps
As described for example 163c, 3-((3-(5-fluoropyridin-2-yl)-5-methylisoxazol-4-yl)methylamino)-1-methyl-1H-pyrazole-5-carboxylic acid (76 mg, 0.23 mol) was converted, using 4-aminotetrahydropyran instead of isopropylamine, to the title compound (95 mg, 80%) which was obtained as a white solid. MS: m/e=415.2 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08163728B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-a04ca6b05d2d480783cfb813fa6ce2ce |
| Source note | uspto-grants-2012_04 |