3,5-Difluorophenylhydrazine hydrochloride → HCID 57965394, compound

HRID 1695545Notes

Reaction equation

HRID 1695545 reaction equation
[OH:1][C@@H:2]1[C@H:15]2[C@@H:6]([CH2:7][CH2:8][C:9]3[C@:14]2([CH3:16])[CH2:13][CH:12]([CH:17]=O)[C:11](=O)[CH:10]=3)[C@@H:5]2[CH2:20][CH2:21][C@:22]3([C:26]4([CH2:30][O:29][CH2:28][O:27]4)[O:25][CH2:24][O:23]3)[C@@:4]2([CH3:31])[CH2:3]1.[F:32][C:33]1[CH:34]=[C:35]([NH:40][NH2:41])[CH:36]=[C:37]([F:39])[CH:38]=1>>[F:32][C:33]1[CH:34]=[C:35]([N:40]2[C:11]3[CH:10]=[C:9]4[CH2:8][CH2:7][C@@H:6]5[C@@H:15]([C@@:14]4([CH3:16])[CH2:13][C:12]=3[CH:17]=[N:41]2)[C@@H:2]([OH:1])[CH2:3][C@:4]2([CH3:31])[C@:22]3([CH2:21][CH2:20][C@@H:5]52)[C:26]2([CH2:30][O:29][CH2:28][O:27]2)[O:25][CH2:24][O:23]3)[CH:36]=[C:37]([F:39])[CH:38]=1

Participants

3

Reactant 2

HCID 27742133,5-Difluorophenylhydrazine hydrochlorideHCID 59810282HCID 59810282, compound

Product 1

HCID 57965394HCID 57965394, compound

Procedure

The compound was prepared from (8S,9S,10R,11S,13S,14S,17R)-11-hydroxy-10,13-dimethyl-3-oxo-1,2,3,6,7,8,9,10,11,12,13,14,15,16-tetradecahydrodispiro[cyclopenta[a]phenanthrene-17,4′-[1,3]dioxolane-5′,4″[1,3]dioxolane]-2-carbaldehyde and (3,5-difluorophenyl)hydrazine according to the procedure for Intermediate 50. APCI-MS m/z: 541 [MH+].

Sources & evidence

ORD record
ord-c1a40353d5394cd8ab24fed6cf19e077
Source dataset
uspto-grants-2012_04
Patent number
US08163724B2

Reaction notes

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