Lithium Hydroxide → HCID 11854276, compound

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Using 4-chlorophenyl-2-amino-acetic acid methyl ester as a primary amine, (4-Chloro-phenyl)-[3-(4-chloro-phenyl)-4-(2-methoxy-ethylcarbamoyl)-1-oxo-3,4-dihydro-1H-isoquinolin-2-yl]-acetic acid methyl ester was prepared according to the general procedure of example 1 and 3. The final acid (4-Chloro-phenyl)-[3-(4-chloro-phenyl)-4-(2-methoxy-ethylcarbamoyl)-1-oxo-3,4-dihydro-1H-isoquinolin-2-yl]-acetic acid was prepared by treatment with lithium hydroxide in tetrahydrofuran. Molecular Weight=527.4087, calculated from Molecular Formula=C27H24Cl2N2O5. ([M+H]+) observed 526.9.

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