HuagongsheHuagongshe Chemistry Print Report · For research reference only
(R)-(-)-1-Aminoindan → HCID 178526446, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (R)-(-)-1-Aminoindan | HCID 2733933 | — |
| Reactant | tert-Butyl-(2-isothiocyanato-5-nitro-benzyloxy)-dimethyl-silane | HCID 46855450 | — |
| Product | HCID 178526446 | HCID 178526446 | 93% |
Reaction Steps
Prepared from tert-butyl-(2-isothiocyanato-5-nitro-benzyloxy)-dimethyl-silane (Example C1) (3.89 g, 12.0 mmol; HPLC: 4.446 min) and commercially available (R)-(−)-1-aminoindane (1.54 mL, 12.0 mmol; HPLC 0.4 min) according to the procedure described for Example 1. Obtained the title compound as a yellow foam (3.45 g, 93%; HPLC 1.954 min), MS (ISN) m/e=308.5 [(M−H)−].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08163740B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-0ede6a3e947e47ddaa02afb4c83d82d5 |
| Source note | uspto-grants-2012_04 |