HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Fluoro-2,3-dihydro-1H-inden-1-amine → HCID 178526440, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Fluoro-2,3-dihydro-1H-inden-1-amine | HCID 16666328 | — |
| Reactant | tert-Butyl-(2-isothiocyanato-5-nitro-benzyloxy)-dimethyl-silane | HCID 46855450 | — |
| Product | HCID 178526440 | HCID 178526440 | 90% |
Reaction Steps
Prepared from tert-butyl-(2-isothiocyanato-5-nitro-benzyloxy)-dimethyl-silane (Example C1) (1.22 g, 3.76 mmol; HPLC: 4.446 min) and rac-5-fluoro-indan-1-ylamine (CAS 148960-33-2) (568 mg, 3.76 mmol; HPLC 0.4 min) according to the procedure described for Example 1. Obtained the title compound as a yellow solid (0.93 g, 90%), MS (ISP) m/e=328.2 [(M+H)+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08163740B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-db42932d115440dbaf42367b8516f63e |
| Source note | uspto-grants-2012_04 |