Chloroacetyl chloride → HCID 178489487, compound

Participants

Reaction Steps

Prepared from N2-(2-methoxy-benzyl)-4H-benzo[d][1,3]oxazine-2,6-diamine (Example 4) (1.26 g, 4.45 mmol) and chloroacetyl chloride (0.39 ml, 4.89 mmol) according to the procedure described for Example 17. Obtained the title compound as a white solid (842 mg, 42%, HPLC 0.889 min 81%), MS (ISP) m/e=360.3 [(M+H)+] and 362.1 [(M+2+H)+].

Provenance & Evidence