HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Methoxy-2,3-dihydrobenzofuran-3-amine → HCID 178488327, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Methoxy-2,3-dihydrobenzofuran-3-amine | HCID 67212522 | — |
| Reactant | (5-Bromo-2-isothiocyanato-benzyloxy)-tert-butyl-dimethyl-silane | HCID 87311762 | — |
| Product | HCID 178488327 | HCID 178488327 | 50% |
Reaction Steps
Prepared from (5-bromo-2-isothiocyanato-benzyloxy)-tert-butyl-dimethyl-silane (Example 32, step B) (4.0 g, 11.2 mmol) and rac-4-methoxy-2,3-dihydro-benzofuran-3-ylamine (Example 5, step B) (1.84 g, 11.2 mmol) according to the procedure described for Example 1. Obtained the title compound as a white solid (2.09 g, 50%), m.p. 132.5° C.; MS (ISP) m/e=375.1 [(M+H)+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08163740B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-551518b1aedd4dd9ad48d47d0ee41f83 |
| Source note | uspto-grants-2012_04 |