HRID1695632

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID795

Imidazole

C3H4N2

结构：O=C(CCl)Nc1ccc2c(c1)COC(N[C@@H]1CCc3ccccc31)=N2

HCID178520800

未命名化合物

PRODUCTS

生成物

结构：O=C(Cn1ccnc1)Nc1ccc2c(c1)COC(N[C@@H]1CCc3ccccc31)=N2

HCID178521199

未命名化合物

收率 73.5%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID6342

Acetonitrile

C2H3N

PROCEDURE

实验过程

Prepared from 2-chloro-N-[2-((R)-indan-1-ylamino)-4H-benzo[d][1,3]oxazin-6-yl]-acetamide (Example 3 step A) (100 mg, 0.281 mmol) and imidazole (96 mg, 1.405 mmol) in acetonitrile (1 ml) according to the procedure described for Example 3 step B. Obtained the title compound as a white solid (80 mg, 73%), MS (ISP) m/e=388.3 [(M+H)+].