3,4-Dihydro-2H-1-benzopyran-4-amine → HCID 178526444, compound

Participants

Reaction Steps

Prepared from tert-butyl-(2-isothiocyanato-5-nitro-benzyloxy)-dimethyl-silane (Example C1) (2.271 g, 7.0 mmol; HPLC: 4.446 min) and rac-chroman-4-ylamine (CAS 53981-38-7) (1.044 g, 7.0 mmol; 0.374 min) according to the procedure described for Example 1. Obtained the title compound as a yellow solid (1.98 g, 87%, HPLC 2.031 min), MS (ISP) m/e=326.2 [(M+H)+].

Provenance & Evidence