Chloroacetyl chloride → HCID 178520797, compound

Participants

Reaction Steps

Prepared from rac-N2-chroman-4-yl-4H-benzo[d][1,3]oxazine-2,6-diamine (Example 75) (591 mg, 2.0 mmol) and chloroacetyl chloride (167 ul, 2.1 mmol) according to the procedure described for Example 3 step A. Obtained the title compound as an off-white solid (618 mg, 83%), MS (ISP) m/e=372.1 [(M+H)+] and 374 [(M+2+H)+].

Provenance & Evidence