Morpholine → HCID 178521230, compound

Participants

Reaction Steps

Prepared from rac-2-chloro-N-[2-(chroman-4-ylamino)-4H-benzo[d][1,3]oxazin-6-yl]-acetamide (Example 120, step A) (186 mg, 0.50 mmol; HPLC 1.092 min) and morpholine (0.87 ml, 10 mmol) according to the procedure described for Example 3 step B. Obtained the title compound as a white foam (217 mg, 100%; HPLC 0.504 min), MS (ISP) m/e=423.2 [(M+H)+].

Provenance & Evidence