HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,3-Thiazole-2-carbaldehyde → N2-(3-Cyclopropyl-phenyl)-N6-thiazol-2-ylmethyl-4H-benzo[d][1,3]oxazine-2,6-diamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,3-Thiazole-2-carbaldehyde | HCID 2734903 | — |
| Reactant | N2-(3-cyclopropyl-phenyl)-4H-benzo[d][1,3]oxazine-2,6-diamine | HCID 59231769 | — |
| Product | N2-(3-Cyclopropyl-phenyl)-N6-thiazol-2-ylmethyl-4H-benzo[d][1,3]oxazine-2,6-diamine | HCID 59231801 | 46.1% |
Reaction Steps
Prepared from N2-(3-cyclopropyl-phenyl)-4H-benzo[d][1,3]oxazine-2,6-diamine (158 mg, 0.57 mmol) and 2-formylthiazole (70 mg, 0.62 mmol) according to the procedure described for example 88. Obtained the title compound as a yellow foam (99 mg, 46%), MS (ISP) m/e=377.2 [(M−H)+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08163740B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-e18b3eb7a20f4212b9d93d8436dfcdf1 |
| Source note | uspto-grants-2012_04 |