Cyclopropanecarboxylic acid → Cyclopropanecarboxylic acid [2-(3-cyclopropyl-phenylamino)-4H-benzo[d][1,3]oxazin-6-yl]-amide

Participants

Role	Name	HCID	Charge
Reactant	Cyclopropanecarboxylic acid	HCID 15655	—
Reactant	N2-(3-cyclopropyl-phenyl)-4H-benzo[d][1,3]oxazine-2,6-diamine	HCID 59231769	—
Product	Cyclopropanecarboxylic acid [2-(3-cyclopropyl-phenylamino)-4H-benzo[d][1,3]oxazin-6-yl]-amide	HCID 67277068	37.2%

Reaction Steps

Prepared from N2-(3-cyclopropyl-phenyl)-4H-benzo[d][1,3]oxazine-2,6-diamine (200 mg, 0.72 mmol) and and cyclopropane carboxylic acid (80 mg, 0.93 mmol) according to the procedure described for example 93. Obtained the title compound as a white solid (93 mg, 37%),

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08163740B2
Source dataset	uspto-grants-2012_04
ORD ID	ord-55e9a9d7f4a44535807fc6ca8233def0
Source note	uspto-grants-2012_04