1H-imidazole-2-carbaldehyde → HCID 59231762, compound

HRID 1695681Notes

Reaction equation

HRID 1695681 reaction equation
[CH3:1][C:2]1([CH3:23])[CH2:6][C:5]2[CH:7]=[CH:8][CH:9]=[C:10]([NH:11][C:12]3[O:13][CH2:14][C:15]4[CH:21]=[C:20]([NH2:22])[CH:19]=[CH:18][C:16]=4[N:17]=3)[C:4]=2[O:3]1.[NH:24]1[CH:28]=[CH:27][N:26]=[C:25]1[CH:29]=O>>[CH3:1][C:2]1([CH3:23])[CH2:6][C:5]2[CH:7]=[CH:8][CH:9]=[C:10]([NH:11][C:12]3[O:13][CH2:14][C:15]4[CH:21]=[C:20]([NH:22][CH2:29][C:25]5[NH:24][CH:28]=[CH:27][N:26]=5)[CH:19]=[CH:18][C:16]=4[N:17]=3)[C:4]=2[O:3]1

Participants

3

Reactant 2

HCID 249551H-imidazole-2-carbaldehydeHCID 86639787HCID 86639787, compound

Product 1

HCID 59231762HCID 59231762, compound

Procedure

Prepared from N2-(2,2-dimethyl-2,3-dihydro-benzofuran-7-yl)-4H-benzo[d][1,3]oxazine-2,6-diamine (example 139, step B) and 2-imidazolecarboxaldehyde according to the procedure described for example 88. The title compound was obtained as a brown solid, MS (ISP) m/e=390.3 [(M+H)+].

Sources & evidence

ORD record
ord-119c7e65b0ce4053a41eb91502923bf0
Source dataset
uspto-grants-2012_04
Patent number
US08163740B2

Reaction notes

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