Dimethylsulphamoyl chloride → N'-{2-[(3-cyclopropylphenyl)amino]-4H-benzo[d][1,3]oxazin-6-yl}-N,N-dimethylsulfamide

Participants

Role	Name	HCID	Charge
Reactant	Dimethylsulphamoyl chloride	HCID 83372	—
Reactant	N2-(3-cyclopropyl-phenyl)-4H-benzo[d][1,3]oxazine-2,6-diamine	HCID 59231769	—
Product	N'-{2-[(3-cyclopropylphenyl)amino]-4H-benzo[d][1,3]oxazin-6-yl}-N,N-dimethylsulfamide	HCID 59231768	37.4%

Reaction Steps

Prepared from N2-(3-cyclopropyl-phenyl)-4H-benzo[d][1,3]oxazine-2,6-diamine (200 mg, 0.72 mmol) and dimethylsulfamoyl chloride (122 mg, 0.85 mmol) according to the procedure described for example 27. Obtained the title compound as an off-white foam (104 mg, 37%), MS (ISP) m/e=385.3 [(M−H)+].

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08163740B2
Source dataset	uspto-grants-2012_04
ORD ID	ord-1f17496aa2a84d1d937b411f537c4bcc
Source note	uspto-grants-2012_04