HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclopropanesulfonyl chloride → Cyclopropanesulfonic acid [2-(3-cyclopropyl-phenylamino)-4H-benzo[d][1,3]oxazin-6-yl]-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclopropanesulfonyl chloride | HCID 2760919 | — |
| Reactant | N2-(3-cyclopropyl-phenyl)-4H-benzo[d][1,3]oxazine-2,6-diamine | HCID 59231769 | — |
| Product | Cyclopropanesulfonic acid [2-(3-cyclopropyl-phenylamino)-4H-benzo[d][1,3]oxazin-6-yl]-amide | HCID 59231789 | 9.1% |
Reaction Steps
Prepared from N2-(3-Cyclopropyl-phenyl)-4H-benzo[d][1,3]oxazine-2,6-diamine (Example 119) (200 mg, 0.72 mmol) and cyclopropanesulfonyl chloride (161 mg, 1.1 mmol) according to the procedure described for Example 27. Obtained the title compound as an off-white foam (25 mg, 9%), MS (ISP) m/e=382.4 [(M−H)−].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08163740B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-6cc7af5b3bf948e99fc95ef06d760a0e |
| Source note | uspto-grants-2012_04 |