HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzenesulfonyl chloride, 2,5-dimethyl- → HCID 86653307, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzenesulfonyl chloride, 2,5-dimethyl- | HCID 87910 | — |
| Reactant | 3-Amino-5-bromo-2-chloropyridine | HCID 21858354 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | HCID 86653307 | HCID 86653307 | 47.8% |
Reaction Steps
3-Amino-5-bromo-2-chloropyridine (510 mg) in dry pyridine (7 ml) was treated with 2,5-dimethylbenzenesulfonyl chloride (962 mg) then stirred at RT overnight. The reaction was purified by prep-HPLC. The combined fractions were concentrated to give a slurry, then filtered, rising with water and dried overnight to give title compound (441 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08163743B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-05841f86cc6b4fae8cea773a20ab96c3 |
| Source note | uspto-grants-2012_04 |