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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 169579Generated: October 25, 2026

Dimethylformamide → 2-(4-(2-hydroxy-2-methylpropoxy)-3-methoxyphenyl)-5-(4-(trifluoromethyl)-phenyl)pyridazin-3(2H)-one

https://huagongshe.com/reaction/169579

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
ReactantDichloromethaneHCID 6344—
ReactantN,N'-DimethylethylenediamineHCID 8070—
ReactantCopper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 24350—
Reactant5-(4-(Trifluoromethyl)phenyl)pyridazin-3(2H)-oneHCID 57950387—
Reactant1-(4-Bromo-2-methoxyphenoxy)-2-methylpropan-2-olHCID 59595049—
Product2-(4-(2-hydroxy-2-methylpropoxy)-3-methoxyphenyl)-5-(4-(trifluoromethyl)-phenyl)pyridazin-3(2H)-oneHCID 46927506—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-5555f5de8454470d900153e7d1ccf95a
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)