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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1696219Generated: November 1, 2026

HCID 67277937, compound → HCID 67278403, compound

https://huagongshe.com/reaction/1696219

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 67277937HCID 67277937—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 67278403HCID 67278403101%

Reaction Steps

To a solution of benzyl 4-{[trans-3-carbamoylcyclohexyl]amino}-1H-pyrrolo[2,3-b]pyridine-5-carboxylate (36 mg) in dioxane (7 ml) and methanol (7 ml) was added 10% Pd—C (50% wet) (10 mg) and stirred at ambient temperature for 3 hours under hydrogen atmosphere. After filtration the filtrate was evaporated in vacuo to give 4-{[trans-3-carbamoylcyclohexyl]amino}-1H-pyrrolo[2,3-b]pyridine-5-carboxylic acid (28 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08163767B2
Source datasetuspto-grants-2012_04
ORD IDord-c13dd5060a904d2f9f678bf4b9443960
Source noteuspto-grants-2012_04