HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 5-bromo-1-cyclopentyl-6-oxo-1,6-dihydropyridine-3-carboxylate → Methyl 1-cyclopentyl-6-oxo-1,6-dihydropyridine-3-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 5-bromo-1-cyclopentyl-6-oxo-1,6-dihydropyridine-3-carboxylate | HCID 15946267 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | Methyl 1-cyclopentyl-6-oxo-1,6-dihydropyridine-3-carboxylate | HCID 66844659 | — |
Reaction Steps
Through a solution of methyl 5-bromo-1-cyclopentyl-6-oxo-1,6-dihydropyridine-3-carboxylate (300 mg, 1 mmol) and Pd/C (300 mg) in methanol (30 mL) was bubbled H2 through a balloon for 48 h. The mixture was filtered through Celite® and concentrated to afford the title compound. MS m/z: 222 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08163766B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-718cb77cafc54bb9adc5527359b9ac98 |
| Source note | uspto-grants-2012_04 |