HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl (3-nitrophenyl)acetate → Ethyl 2-(3-aminophenyl)acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl (3-nitrophenyl)acetate | HCID 14997011 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | Ethyl 2-(3-aminophenyl)acetate | HCID 13042040 | 94.9% |
Reaction Steps
A mixture of ethyl (3-nitrophenyl)acetate (21 g, 0.1 mol) and 10% Pd/C (2 g) in MeOH (300 mL) was stirred at RT under H2 40 (psi) for 2 h. The reaction mixture was filtered and the filtrate was concentrated to afford ethyl (3-aminophenyl)acetate (17 g). MS (ESI) m/z: 180 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08163756B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-e649c546a045455fbf792655a090ceee |
| Source note | uspto-grants-2012_04 |