m-Chloroperbenzoic acid → HCID 67276635, compound

Participants

Reaction Steps

M-chloroperbenzoic acid (content, 65% or more, 200 mg) was added to a chloroform (2 mL) solution of 4-(3-methyl-1,4-benzoxathiin-2-yl)phenol (100 mg, 0.39 mmol) synthesized in Reference Example 1-2, and stirred at room temperature for 90 minutes. Aqueous saturated sodium hydrogensulfite solution and aqueous saturated sodium hydrogencarbonate solution were added to the reaction solution, and stirred. The organic layer was collected, dried with magnesium sulfate, and concentrated under reduced pressure to obtain the entitled compound (106 mg, 94%).

Provenance & Evidence